Once an enemy starts wailing on you with a combo, you can usually still start blocking partway through and avoid some damage or getting knocked down.
For example Beast lets you repeatedly grab and slam an enemy to the ground, and one of the Breaker combo finishers deals massive damage to a grounded opponent.
When you first get to move freely in the city in Chapter 1, stock up on some healing items from the drug store to make an early boss fight easier.Hold X to dash and R1 + X (or whichever equivalents) to fast forward text.
There is no autosave, so make sure to save often.Check the in-game Notebook for a variety of useful gameplay tips not listed here.Things to Know Before Playing General Tips